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cpg oligonucleotide  (InvivoGen)


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    Structured Review

    InvivoGen cpg oligonucleotide
    Cpg Oligonucleotide, supplied by InvivoGen, used in various techniques. Bioz Stars score: 98/100, based on 1325 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cpg+odn+1826+oligonucleotide+cpg/ODN+1826/pm41574728-244-0-7
    Average 98 stars, based on 1325 article reviews
    cpg oligonucleotide - by Bioz Stars, 2026-10
    98/100 stars

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    other:

    Article Title: Innate imprinting of transcriptional trajectories governs respiratory T RM fate and persistence.
    Article Snippet: The 2′3′-cGAMP VacciGrade (CDN) and CpG ODN 1826 oligonucleotide (CpG) were purchased from InvivoGen (San Diego, CA).



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    a, Schematic depicting experimental setup for CpG <t>ODN1826-induced</t> inflammation. b, Itaconate, mesaconate, and 2HMS abundances in plasma. c, Itaconate abundance in tissues d, Mesaconate abundance in tissues. e , 2HMS abundance in tissues. f , 2HMS relative to mesaconate levels in CpG-treated liver and BAT tissues g, Irg1 expression level in liver and BAT tissue. h , Auh and Slc13a3 expression level in liver and BAT tissue. i , Auh expression in various tissues (Schaum et al., Nature, 2020). j , Schematic depicting itaconate degradation pathways in liver and adipose tissue with distinct pathways for mesaconate and 2HMS synthesis. Data are presented as box (25 th to 75 th percentile with median line) and whiskers (min. to max. values). Animals were injected with 200 µg CpG <t>oligonucleotide</t> every second day for a total of 5 injections (ODN, n = 5) and compared to control conditions (Ctr, n = 5). Schematics in and were prepared with Biorender. BAT, brown adipose tissue; scWAT, subcutaneous white adipose tissue; gWAT, gonadal white adipose tissue. P values were calculated by multiple unpaired t -test (b-e), unpaired t -test (f), one-way ANOVA (g), or two-way ANOVA compared to Ctr (h) with * p < 0.05; ** p < 0.01, *** p < 0.001, # p < 0.0001.
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    a, Schematic depicting experimental setup for CpG <t>ODN1826-induced</t> inflammation. b, Itaconate, mesaconate, and 2HMS abundances in plasma. c, Itaconate abundance in tissues d, Mesaconate abundance in tissues. e , 2HMS abundance in tissues. f , 2HMS relative to mesaconate levels in CpG-treated liver and BAT tissues g, Irg1 expression level in liver and BAT tissue. h , Auh and Slc13a3 expression level in liver and BAT tissue. i , Auh expression in various tissues (Schaum et al., Nature, 2020). j , Schematic depicting itaconate degradation pathways in liver and adipose tissue with distinct pathways for mesaconate and 2HMS synthesis. Data are presented as box (25 th to 75 th percentile with median line) and whiskers (min. to max. values). Animals were injected with 200 µg CpG <t>oligonucleotide</t> every second day for a total of 5 injections (ODN, n = 5) and compared to control conditions (Ctr, n = 5). Schematics in and were prepared with Biorender. BAT, brown adipose tissue; scWAT, subcutaneous white adipose tissue; gWAT, gonadal white adipose tissue. P values were calculated by multiple unpaired t -test (b-e), unpaired t -test (f), one-way ANOVA (g), or two-way ANOVA compared to Ctr (h) with * p < 0.05; ** p < 0.01, *** p < 0.001, # p < 0.0001.
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    Image Search Results


    a, Schematic depicting experimental setup for CpG ODN1826-induced inflammation. b, Itaconate, mesaconate, and 2HMS abundances in plasma. c, Itaconate abundance in tissues d, Mesaconate abundance in tissues. e , 2HMS abundance in tissues. f , 2HMS relative to mesaconate levels in CpG-treated liver and BAT tissues g, Irg1 expression level in liver and BAT tissue. h , Auh and Slc13a3 expression level in liver and BAT tissue. i , Auh expression in various tissues (Schaum et al., Nature, 2020). j , Schematic depicting itaconate degradation pathways in liver and adipose tissue with distinct pathways for mesaconate and 2HMS synthesis. Data are presented as box (25 th to 75 th percentile with median line) and whiskers (min. to max. values). Animals were injected with 200 µg CpG oligonucleotide every second day for a total of 5 injections (ODN, n = 5) and compared to control conditions (Ctr, n = 5). Schematics in and were prepared with Biorender. BAT, brown adipose tissue; scWAT, subcutaneous white adipose tissue; gWAT, gonadal white adipose tissue. P values were calculated by multiple unpaired t -test (b-e), unpaired t -test (f), one-way ANOVA (g), or two-way ANOVA compared to Ctr (h) with * p < 0.05; ** p < 0.01, *** p < 0.001, # p < 0.0001.

    Journal: bioRxiv

    Article Title: Itaconate is metabolized to 2-hydroxymethylsuccinate through a CoA-independent degradation pathway in mitochondria

    doi: 10.1101/2025.09.29.679238

    Figure Lengend Snippet: a, Schematic depicting experimental setup for CpG ODN1826-induced inflammation. b, Itaconate, mesaconate, and 2HMS abundances in plasma. c, Itaconate abundance in tissues d, Mesaconate abundance in tissues. e , 2HMS abundance in tissues. f , 2HMS relative to mesaconate levels in CpG-treated liver and BAT tissues g, Irg1 expression level in liver and BAT tissue. h , Auh and Slc13a3 expression level in liver and BAT tissue. i , Auh expression in various tissues (Schaum et al., Nature, 2020). j , Schematic depicting itaconate degradation pathways in liver and adipose tissue with distinct pathways for mesaconate and 2HMS synthesis. Data are presented as box (25 th to 75 th percentile with median line) and whiskers (min. to max. values). Animals were injected with 200 µg CpG oligonucleotide every second day for a total of 5 injections (ODN, n = 5) and compared to control conditions (Ctr, n = 5). Schematics in and were prepared with Biorender. BAT, brown adipose tissue; scWAT, subcutaneous white adipose tissue; gWAT, gonadal white adipose tissue. P values were calculated by multiple unpaired t -test (b-e), unpaired t -test (f), one-way ANOVA (g), or two-way ANOVA compared to Ctr (h) with * p < 0.05; ** p < 0.01, *** p < 0.001, # p < 0.0001.

    Article Snippet: The CpG oligonucleotide (ODN1826 sodium salt, MCE, Cat.# HY-1416245C) was dissolved in dPBS to a concentration of 1 mg/ml and filtered using a 0.2 μm PTFE syringe filter (Fisher Scientific, Cat.# 15342378).

    Techniques: Clinical Proteomics, Expressing, Injection, Control